EMPreSS (Epithelial Mesenchymal Precision Spectrum Scoring)
Principal Investigator : Prof. Ruby Yun-Ju HUANG
Team Size : 13
Study Field : Fluidity of Transition, Genome Architecture, Spatial Context of EMT
Forms of Int'l Cooperation : Joint Research Project, Personnel Exchange, Seminar
Lab Introduction
EMPreSS (Epithelial Mesenchymal Precision Spectrum Scoring) is a new system to assess the epithelial and mesenchymal states from the concept of a spectrum beyond the traditional binary perspective.
Our fundamental questions are:
What makes the epithelial, epithelial?
What is the precise estimation of “mesenchymality”?
What is the fluidity of the interchange among different states?
Acknowledging the existence of EMT as a spectrum, solving the heterogeneity of EMT thus becomes an inevitable task. Our lab takes several approaches to dissect the heterogeneity of EMT from multiple dimensions: (1) the fluidity of transition; (2) the genome architecture; (3) the spatial context.
International Cooperation Experience
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European Commission, Joint Research Centre (JRC); Department of Translational Biomedicine and Neurosciences, University of Bari Aldo Moro | ItalyJoint Research Project Personnel Exchange
2022 ~ present
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Universidade do Porto | PortugalJoint Research Project Personnel Exchange
2022 ~ present
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Friedrich-Alexander-Universität Erlangen-Nürnberg; University Hospital Duesseldorf; Research Center Université Grenoble Alpes; Inserm; CNRS; Ulm University Medical Center | GermanyJoint Research Project Personnel Exchange
2022 ~ present
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National University of Singapore; National University Hospital | SingaporeJoint Research Project Personnel Exchange
2019 ~ present
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University College London; The Christie NHS Foundation Trust; University of Manchester | United KingdomJoint Research Project Personnel Exchange
2022 ~ present
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University of Queensland | AustraliaJoint Research Project
2021 ~ 2023
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Postgraduate Program of Health Sciences, School of Medicine, Pontifícia; Universidade Católica do Paraná ́-PUCPR | BrazilPersonnel Exchange
2021 ~ 2023
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BioMimetic Systems Engineering Lab, School of Chemical Engineering, University of Queensland; Frazer Institute, Faculty of Medicine, The University of Queensland | AustraliaJoint Research Project
2021 ~ 2023
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QIMR Berghofer Medical Research Institute; QCIF Bioinformatics | AustraliaJoint Research Project
2021 ~ 2023
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School of Life Sciences & Institute for Biomedical Materials and Devices, Faculty of Science, University of Technology Sydney | AustraliaPersonnel Exchange
2021 ~ 2023
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Faculty of Health Sciences and Medicine, Bond University; Centre for Genomics and Personalised Health, School of Biomedical Sciences, Queensland University of Technology | AustraliaPersonnel Exchange
2021 ~ 2023
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Guangzhou Regenerative Medicine and Health, Guangdong Laboratory | Mainland ChinaJoint Research Project
2020 ~ 2022
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Kyoto University; RIKEN; Kumamoto University | JapanJoint Research Project
2020 ~ 2022
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Institute of Electromagnetic Fields , ETH Zürich (Swiss Federal Institute of Technology in Zürich); Competence Center for Applied Biotechnology and Molecular Medicine, University of Zürich | SwitzerlandPersonnel Exchange
2020 ~ 2022
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Institute for Research in Biomedicine (IRB Barcelona); Barcelona Institute of Science and Technology; Institut de Biologia Molecular de Barcelona (IBMB-CSIC) | SpainPersonnel Exchange
2020 ~ 2022
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Nanostring Technologies | United States of AmericaJoint Research Project Personnel Exchange Seminar
2021 ~ 2022
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Department of Biochemistry and Molecular Biology, University of British Columbia; British Columbia Cancer Research Centre | CanadaPersonnel Exchange
2021 ~ 2022
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Molecular and Cellular Oncology Lab, Department of Biomedical Molecular Biology, Ghent University, Cancer Research Institute Ghent (CRIG), VIB Center for Inflammation Research; Laboratory of Stem Cells and Cancer, Université Libre de Bruxelles | BelgiumPersonnel Exchange
2020 ~ 2021
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Institut Curie, PSL Research University; Université Claude Bernard Lyon 1; Cancer Research Center of Lyon | FranceJoint Research Project
2019 ~ 2021
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Department of Medical Neurobiology, Institute for medical Research Israel-Canada; the Safra Center for Neurosciences, Hebrew University of Jerusalem, Hadassah Medical School | IsraelJoint Research Project
2019 ~ 2021
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Department of Laboratory Medicine (LABMED), Division of Pathology, Karolinska University Hospital; Department of Microbiology, Tumor and Cell Biology (MTC) | SwedenPersonnel Exchange
2019 ~ 2021
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Translational Research Collective, Faculty of Medicine and health, Brain & Mind Centre, University of Sydney | AustraliaJoint Research Project Personnel Exchange
2020 ~ 2021
Contact
Yi Chia CHIU
Position : Research Associate
Email : ycchiu11@ntu.edu.tw
Phone : +8862-2312-3456 #288398
Ko Chen CHEN
Position : Research Associate
Email : kochenchen@ntu.edu.tw
Phone : +8862-2312-3456 #288264
Principal Investigator
Position : Professor, College of Medicine
Email : rubyhuang@ntu.edu.tw
Education / Background :
