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College of Life Science

Fundamental Neuronal Physiology and Behavior Research Group

Official Website

Principal Investigator : Prof. Shih-Kuo CHEN

Team Size : 4

Study Field : Neuroinflammation and Neurodegeneration of Cultured Neurons; Fighting Response and Depression of Zebrafish; Intrinsically Photosensitive Retinal Ganglion Cell and Circadian Rhythm of Mice

Interested International Cooperation : Joint Research Project, Personnel Exchange, Student Exchange, Seminar

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Lab Introduction

The nervous system integrates single neurons' activities to respond to environmental stimuli with behaviors. Basic neuronal circuits like the knee reflex involve several neurons; however, complex behaviors and cognitive functions need cooperation among different brain regions. We integrate various laboratories' expertise and model systems, from cultured neurons to zebrafish and mouse models, to connect the neuronal functions at the molecular and cellular levels to behavioral activities. We routinely use electrophysiology, neuronal (stem) cell culture, adenovirus infection, brain slice recording, in vivo 2-photon ion imaging, and behaviors of zebrafish and mice. The research topics we currently focus on are neuroinflammation and neurodegeneration of cultured neurons; fighting response and depression of zebrafish; intrinsically photosensitive retinal ganglion cell and the circadian rhythm of mice. 

International Cooperation Experience

  • | Establish a New Model of Intellectual Disability to Study Human Novel Disease Gene in Zebrafish | Thailand
    Joint Research Project Personnel Exchange Student Exchange

    2020 ~ present

  • | Neuroscience Summer Camp | Japan
    Personnel Exchange Student Exchange

    2006 ~ present

  • Kyoto University; University of Tsukuba | Mini-symposium of Cellular and Molecular Biology | Japan
    Seminar

    2005 ~ present

Contact

Prof. Chien-Yuan PAN

Position : Professor

Email : cypan@ntu.edu.tw

Phone : +8862-3366-2452

Principal Investigator

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Prof. Shih-Kuo CHEN

Position : Professor, Department of Life Science

Email : alenskchen@ntu.edu.tw

Education / Background :

  • PhD, Department of Biology and Biochemistry, University of Houston, USA
  • B.S., Department of Zoology, National Taiwan University, Taiwan
     

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