A new meta-analysis shows that when people eat may be as important as how long they eat. Eating earlier in the day appears to support better metabolic health than eating late, even within time-restricted eating patterns.
Time-restricted eating has emerged as a popular dietary approach because it focuses on when people eat rather than strictly limiting calories. Instead of counting calories, individuals restrict their daily food intake to a defined time window. While this approach has been widely studied, most research has focused on whether time-restricted eating works, with less attention paid to how eating timing and eating duration interact.
In a new comprehensive analysis of randomized controlled trials from around the world, researchers at National Taiwan University examined time-restricted eating in greater detail. Rather than treating all time-restricted eating patterns as equivalent, the study, published in BMJ Medicine, explored how both the timing of eating during the day and the length of the eating window influence metabolic health, independently and in combination.
Overall, time-restricted eating was found to be effective in improving metabolic health compared with usual diets. Its benefits were comparable to those of other structured dietary strategies, and many studies reported higher adherence than traditional continuous calorie restriction. This suggests that time-restricted eating may be a more feasible option for many people in real-world settings.
However, not all time-restricted eating patterns performed equally well. Eating earlier or in the middle of the day consistently led to more favorable metabolic outcomes than eating late. Measures related to blood sugar regulation, body weight, and cardiovascular health tended to improve more when food intake was aligned earlier in the day.
The length of the eating window alone showed mixed effects. Shorter eating windows were not universally superior. When eating timing and duration were examined together, poorer outcomes were driven primarily by eating late in the day combined with longer eating windows. In contrast, late eating with shorter windows did not show the same consistently unfavorable pattern.
These findings highlight an important principle of chrono-nutrition: human metabolism follows daily biological rhythms, and the body is better equipped to process food earlier in the day. Aligning food intake with these rhythms appears to play a key role in metabolic health.
“Time-restricted eating can be effective and achievable for many people, but our findings suggest that timing matters,” says Prof. Ling-Wei Chen, senior author of the study.
“Rather than focusing only on how long people eat, aligning food intake earlier in the day may be important for maximizing metabolic benefits.”
Prof. Ling-Wei Chen's email address: lingweichen@ntu.edu.tw
Prof. Chen’s lab: https://ling-weichen.wixsite.com/chenlab
To see article on Asia Research News: https://www.asiaresearchnews.com/content/meal-timing-time-restricted-eating-matters-metabolic-health